SCHEMBL12377040

SCHEMBL12377040

CC1CCC(OC(=O)C2CCC(C)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.41
MAPT P10636 3/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
EPHX1 P07099 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HCRTR2 O43614 1/20 0.32
FABP7 O15540 1/20 0.31
FABP5 Q01469 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SERPINE1 P05121 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152479 1.00 CYP19A1 (0.41) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL20152476 1.00 CYP19A1 (0.41) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL20275995 1.00 CYP19A1 (0.41) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL20276012 1.00 CYP19A1 (0.41) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL20152474 1.00 CYP19A1 (0.41) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL170528 0.94 CYP19A1 (0.38) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL14274401 0.94 CYP19A1 (0.38) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL20152489 0.94 CYP19A1 (0.38) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL14465468 0.94 CYP19A1 (0.38) CYP19A1MAPTRAB9ANPC1ALDH1A1
SCHEMBL13074339 0.94 CYP19A1 (0.38) CYP19A1MAPTRAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023199989-A1 LIGHT DIMMING DEVICE 凸版印刷株式会社 2023-10-19 WO disclosed
US-20230231270-A1 Separator and Application Thereof MICROCOSM TECHNOLOGY CO., LTD. (TW) 2023-07-20 US disclosed
EP-4213290-A2 SEPARATOR AND APPLICATION THEREOF Microcosm Technology Co., Ltd. (TW) 2023-07-19 EP disclosed
US-20180171229-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2018-06-21 US disclosed
US-20180171234-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-06-21 US disclosed
US-20180134961-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-05-17 US disclosed
EP-1618101-B1 BENZOCHROMENE DERIVATIVES MERCK PATENT GMBH (DE) 2017-12-20 EP disclosed
EP-3130650-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-02-15 EP disclosed
WO-2017008884-A1 METHOD OF REDUCING ODF MURA IN POLYMER STABILISED LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2017-01-19 WO disclosed
US-9238775-B2 Switch element comprising a liquid-crystalline medium MERCK PATENT GMBH (DE) 2016-01-19 US disclosed
US-7335404-B2 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-02-26 US disclosed
US-7326447-B2 Benzochromene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-02-05 US disclosed
US-20080020148-A1 Chromane Derivatives Method for Production and the Use Thereof MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-01-24 US disclosed
US-7314653-B2 Liquid-crystal medium and electro-optical display containing same MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-01-01 US disclosed
US-7294368-B2 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-11-13 US disclosed
US-7270856-B2 Cyclobutane derivatives MERCK PATENT GMBH (DE) 2007-09-18 US disclosed
US-7258903-B2 Fast switching liquid crystal compositions for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-08-21 US disclosed
US-20070176144-A1 Liquid crystal composition for bistable liquid crystal devices MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2007-08-02 US disclosed
US-20070080325-A1 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
EP-1567613-B1 CYCLOBUTANE DERIVATIVES MERCK PATENT GMBH (DE) 2007-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080020148-A1 Chromane Derivatives Method for Production and the Use Thereof C1S, CHRM1, C1R CYP19A1 142/4885MAPT 3652/4885RAB9A 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.