SCHEMBL12377556

SCHEMBL12377556

CC(C)=CCC/C(C)=C/CC/C(C)=C/COCc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.59
LSS P48449 2/20 0.53
ICMT O60725 1/20 0.47
KMT2A Q03164 1/20 0.47
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11039509 1.00 TRPV1 (0.59) TRPV1LSSICMTKMT2AFNTA
SCHEMBL11039511 1.00 TRPV1 (0.59) TRPV1LSSICMTKMT2AFNTA
SCHEMBL795297 0.98 TRPV1 (0.60) TRPV1LSSICMTALOX15
SCHEMBL795298 0.98 TRPV1 (0.60) TRPV1LSSICMTALOX15
SCHEMBL1072281 0.90 LSS (0.52) TRPV1LSSICMT
SCHEMBL10981272 0.90 LSS (0.52) TRPV1LSSICMT
SCHEMBL1072282 0.90 LSS (0.52) TRPV1LSSICMT
SCHEMBL10981275 0.90 LSS (0.52) TRPV1LSSICMT
SCHEMBL12377555 0.90 LSS (0.52) TRPV1LSSICMT
SCHEMBL19420736 0.90 LSS (0.52) TRPV1LSSICMTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018116-B1 VITAMIN K2 INTERMEDIATES KAPPA BIOSCIENCE AS (NO) 2020-10-28 EP disclosed
US-10472314-B2 Process for the preparation of vitamin K2 KAPPA BIOSCIENCE AS (NO) 2019-11-12 US disclosed
US-20170283354-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2017-10-05 US disclosed
US-20170283354-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2017-10-05 US disclosed
EP-3018116-A1 VITAMIN K2 INTERMEDIATES Kappa Bioscience As (NO) 2016-05-11 EP disclosed
EP-2346806-B1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2016-01-06 EP disclosed
US-20150210620-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2015-07-30 US disclosed
US-20150210620-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2015-07-30 US disclosed
US-9012693-B2 Process for the preparation of vitamin K2 KAPPA BIOSCIENCE AS (NO) 2015-04-21 US disclosed
US-9012693-B2 Process for the preparation of vitamin K2 KAPPA BIOSCIENCE AS (NO) 2015-04-21 US disclosed
US-20110207967-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2011-08-25 US disclosed
US-20110207967-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2011-08-25 US disclosed
WO-2010035000-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2010-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10472314-B2 Process for the preparation of vitamin K2 PROC, VKORC1, VKORC1L1 TRPV1 4734/4885LSS 370/4885ICMT 1857/4885
US-20170283354-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 TRPV1 4664/4885LSS 305/4885ICMT 1796/4885
US-20110207967-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 TRPV1 4743/4885LSS 290/4885ICMT 1710/4885
US-20150210620-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 TRPV1 4664/4885LSS 305/4885ICMT 1796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.