SCHEMBL12377962

SCHEMBL12377962

CC(=O)N[C@H]1C(O)[C@@H](O)C(CO)O[C@@H]1OP(=O)(O)OP(=O)(O)OCC1OC(n2ccc(=O)[nH]c2=O)C(O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY14 Q15391 10/20 1.00
P2RY6 Q15077 9/20 0.98
P2RY2 P41231 8/20 0.98
P2RY4 P51582 7/20 0.98
OGT O15294 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396726 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL29441461 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL15433957 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL29397191 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL1521296 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL23344493 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL14281873 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL16138527 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL20718791 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT
SCHEMBL19315974 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4OGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8008252-B2 Factor VII: remodeling and glycoconjugation of Factor VII NOVO NORDISK A/S (DK) 2011-08-30 US disclosed