SCHEMBL12378

SCHEMBL12378

COCc1ccc(C)cc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.61
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
MAOB P27338 3/20 0.48
IDO1 P14902 1/20 0.48
KCNH2 Q12809 1/20 0.45
ACHE P22303 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
PARP10 Q53GL7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29207988 0.97 AGXT (0.58) AGXTCA1CA2CA9MAOB
SCHEMBL12648082 0.93 AGXT (0.54) AGXTCA1CA2CA9MAOB
SCHEMBL12736280 0.93 AGXT (0.54) AGXTCA1CA2CA9MAOB
SCHEMBL9330223 0.89 AGXT (0.50) AGXTCA1CA2CA9MAOB
SCHEMBL134443 0.88 IDO1 (0.46) AGXTMAOBIDO1
SCHEMBL12111797 0.87 AGXT (0.48) AGXTCA1CA2CA9MAOB
SCHEMBL8279908 0.87 MAOB (0.61) AGXTMAOBNPC1RAB9APARP10
SCHEMBL17122445 0.87 AGXT (0.48) AGXTCA1CA2CA9MAOB
SCHEMBL17738603 0.87 KCNH2 (0.50) AGXTCA1CA2CA9MAOB
SCHEMBL17429497 0.85 AGXT (0.47) AGXTCA1CA2CA9MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108817049-B Soil heavy metal treatment facility containing propulsion constriction device 徐州工程学院 2021-07-23 CN claimed
CN-108906870-B Soil heavy metal treatment facility containing temperature-sensing device 徐州工程学院 2021-07-23 CN claimed
CN-108772416-B Soil heavy metal treatment facility containing control system 徐州工程学院 2021-07-16 CN claimed
US-20120288752-A1 ADDITIVE FOR OVERCHARGE PREVENTING OF SECONDARY BATTERY AND NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY INCLUDING THE SAME SAMSUNG CORNING PRECISION MATERIALS CO., LTD. 2012-11-15 US claimed
EP-2523247-A1 Additive for overcharge preventing of secondary battery and non-aqueous electrolyte for secondary battery including the same Samsung Corning Precision Materials Co., Ltd. (KR) 2012-11-14 EP claimed
CN-119569545-A Preparation method of methyl ether compound of fatty alcohol 中国人民解放军军事科学院防化研究院 2025-03-07 CN disclosed
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides ARVINAS OPERATIONS, INC. (US) 2024-07-16 US disclosed
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides ARVINAS OPERATIONS, INC. (US) 2024-07-16 US disclosed
WO-2024134657-A1 PYRROLOPYRIDINE AND PYRROLOPYRIDAZINE BASED COMPOUNDS AND USE THEREOF AS PKR INHIBITORS PROTEKT THERAPEUTICS LTD. (IL) 2024-06-27 WO disclosed
US-11857519-B2 Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide ARVINAS OPERATIONS, INC. (US) 2024-01-02 US disclosed
US-11857519-B2 Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide ARVINAS OPERATIONS, INC. (US) 2024-01-02 US disclosed
US-11834460-B2 Imide-based modulators of proteolysis and associated methods of use YALE UNIVERSITY (US) 2023-12-05 US disclosed
EP-0234467-A2 Electrodeless heterogeneous polypyrrole composite The B.F. GOODRICH Company (US) 1987-09-02 EP disclosed
US-4680236-A Electrodeless heterogeneous polypyrrole composite THE BF GOODRICH COMPANY (US) 1987-07-14 US disclosed
EP-0219091-A2 Pyran derivatives and process for their preparation BASF Aktiengesellschaft (DE) 1987-04-22 EP disclosed
US-4617353-A FORMING POLYPYRROLE IN SOLUTION OF MATRIX POLYMER THE B. F. GOODRICH COMPANY (US) 1986-10-14 US disclosed
US-4539081-A ELECTROCHEMICAL OXIDATION IN ALKANOL CONTAINING SULFONIC ACID BASF AKTIENGESELLSCHAFT (DE) 1985-09-03 US disclosed
EP-0129795-A2 Process for manufacturing benzaldehyde dialkylacetals BASF Aktiengesellschaft (DE) 1985-01-02 EP disclosed
US-4340700-A Process for preparing a phenolic resin from an aralkylene ether and an aromatic aldehyde ALBRIGHT & WILSON LIMITED (GB) 1982-07-20 US disclosed
US-4113782-A CATALYTIC OXIDATION AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides IRAK1, IRAK4, IRAK2 AGXT 3780/4885CA1 2572/4885CA2 4367/4885
US-11857519-B2 Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide CRBN, MDM2, VHL AGXT 2299/4885CA1 2650/4885CA2 4176/4885
US-11834460-B2 Imide-based modulators of proteolysis and associated methods of use CRBN, MDM2, UBE2N AGXT 3958/4885CA1 539/4885CA2 2225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.