Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 8/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.85 |
| ▸ | HPGD | P15428 | 3/20 | 0.85 |
| ▸ | RAB9A | P51151 | 2/20 | 0.85 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.85 |
| ▸ | PKM | P14618 | 3/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684711 | 0.92 | MAPT (1.00) | MAPTKDM4ELMNAHTTMAPK1 | |
| Bromide SCHEMBL18040788 | 0.91 | MAPT (0.98) | MAPTKDM4ELMNAHTTMAPK1 | |
| SCHEMBL1684905 | 0.90 | MAPT (0.84) | MAPTKDM4ELMNAHTTMAPK1 | |
| SCHEMBL1684657 | 0.90 | MAPT (0.84) | MAPTKDM4ELMNAHTTMAPK1 | |
| SCHEMBL1684579 | 0.90 | MAPT (0.84) | MAPTKDM4ELMNAHTTMAPK1 | |
| SCHEMBL12012127 | 0.90 | MAPT (0.98) | MAPTKDM4ELMNAHTTMAPK1 | |
| SCHEMBL12427000 | 0.90 | MAPT (0.84) | MAPTKDM4ELMNAHTTMAPK1 | |
| SCHEMBL1684452 | 0.90 | MAPT (0.82) | MAPTKDM4ELMNAHTTMAPK1 | |
| Bromide SCHEMBL3426202 | 0.89 | MAPT (0.82) | MAPTKDM4ELMNAHTTMAPK1 | |
| Bromide SCHEMBL18040748 | 0.89 | MAPT (0.82) | MAPTKDM4ELMNAHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207751-A1 | HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS | ACEA Therapeutics, Inc. | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207751-A1 | HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS | MKI67, CCNC, NUDC | MAPT 4772/4885KDM4E 3222/4885LMNA 3370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.