Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.49 |
| ▸ | BCR | P11274 | 7/20 | 0.49 |
| ▸ | BRAF | P15056 | 12/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12397411 | 0.94 | ABL1 (0.47) | ABL1BCRBRAFABCG2 | |
| SCHEMBL12397229 | 0.93 | BRAF (0.54) | ABL1BCRBRAF | |
| SCHEMBL12397422 | 0.92 | ABL1 (0.45) | ABL1BCRBRAFABCG2 | |
| SCHEMBL12397697 | 0.91 | BRAF (0.54) | ABL1BCRBRAF | |
| SCHEMBL12397416 | 0.89 | ABCG2 (0.48) | ABL1BCRBRAFABCG2 | |
| SCHEMBL12397405 | 0.87 | BRAF (0.48) | ABL1BCRBRAFABCG2 | |
| SCHEMBL12397413 | 0.87 | ABCG2 (0.46) | ABL1BCRBRAFABCG2 | |
| SCHEMBL12397383 | 0.87 | ABL1 (0.50) | ABL1BCRBRAFABCG2 | |
| SCHEMBL12397347 | 0.85 | ABL1 (0.46) | ABL1BCRBRAF | |
| SCHEMBL12397066 | 0.85 | BRAF (0.54) | ABL1BCRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889665-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889665-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | MKI67, CCNA1, CCNT1 | ABL1 136/4885BCR 922/4885BRAF 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.