Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126280 | 0.86 | GFER (0.43) | ALDH1A1KDM4EGFERMEN1KMT2A | |
| SCHEMBL124252 | 0.86 | GFER (0.31) | ALDH1A1GFERMEN1KMT2AKEAP1 | |
| SCHEMBL124460 | 0.86 | TSHR (0.33) | ALDH1A1KDM4EHPGDGFERMEN1 | |
| SCHEMBL127612 | 0.86 | HCAR2 (0.32) | — | |
| SCHEMBL125211 | 0.85 | TSHR (0.43) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL124157 | 0.85 | GFER (0.33) | GFERNOTUMSORT1 | |
| SCHEMBL123356 | 0.84 | MEN1 (0.36) | ALDH1A1KDM4EGFERMEN1KMT2A | |
| SCHEMBL3432223 | 0.84 | GFER (0.34) | ALDH1A1KDM4EGFERMEN1KMT2A | |
| SCHEMBL124857 | 0.84 | GFER (0.31) | ALDH1A1GFERMEN1KMT2AKEAP1 | |
| SCHEMBL27838164 | 0.78 | POLB (0.43) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461083-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-06-11 | — | — | US | disclosed |
| EP-2265120-B1 | HERBICIDAL COUMPOUNDS | SYNGENTA LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2265120-A1 | HERBICIDAL COUMPOUNDS | Syngenta Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009115788-A1 | HERBICIDAL COUMPOUNDS | SYNGENTA LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | RDX, NQO2, DDT | ALDH1A1 677/4885KDM4E 1231/4885HPGD 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.