Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2164231 | 0.83 | EGFR (0.67) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL2163667 | 0.81 | MEN1 (0.65) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL2164699 | 0.81 | MEN1 (0.57) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL2164245 | 0.79 | MEN1 (0.70) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL2163688 | 0.78 | MEN1 (0.60) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL2164209 | 0.75 | EGFR (0.65) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL3757318 | 0.75 | MEN1 (0.69) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL3751477 | 0.75 | ABCG2 (0.67) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL2163049 | 0.75 | MEN1 (0.56) | MEN1KMT2ARAB9ACTDSP1TDP1 | |
| SCHEMBL3757886 | 0.74 | MEN1 (0.68) | MEN1KMT2ARAB9ACTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349835-B2 | Aromatic ring fused triazine derivatives and uses thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2013-01-08 | — | — | US | disclosed |
| US-20110183972-A1 | AROMATIC RING FUSED TRIAZINE DERIVATIVES AND USES THEREOF | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183972-A1 | AROMATIC RING FUSED TRIAZINE DERIVATIVES AND USES THEREOF | KDR, FLT1, FLT4 | MEN1 2848/4885KMT2A 2444/4885RAB9A 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.