Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | ACP1 | P24666 | 4/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172012 | 0.91 | SLC2A1 (0.54) | PIM1ENPP2PPARGPTPN1ACP1 | |
| SCHEMBL2172015 | 0.91 | SLC2A1 (0.54) | PIM1ENPP2PPARGPTPN1ACP1 | |
| SCHEMBL13624279 | 0.91 | SLC2A1 (0.54) | PIM1ENPP2PPARGPTPN1ACP1 | |
| SCHEMBL2172758 | 0.81 | HSD17B3 (0.51) | ENPP2PPARGPTPN1ACP1AGTR1 | |
| SCHEMBL2172764 | 0.81 | HSD17B3 (0.51) | ENPP2PPARGPTPN1ACP1AGTR1 | |
| SCHEMBL2175489 | 0.75 | SLC2A1 (0.61) | PIM1ENPP2PTPN1ACP1SLC2A1 | |
| SCHEMBL2175486 | 0.75 | SLC2A1 (0.61) | PIM1ENPP2PTPN1ACP1SLC2A1 | |
| SCHEMBL12406497 | 0.75 | SLC2A1 (0.61) | PIM1ENPP2PTPN1ACP1SLC2A1 | |
| SCHEMBL1614982 | 0.74 | SLC2A1 (0.66) | PIM1ENPP2PPARGPTPN1ACP1 | |
| SCHEMBL2171655 | 0.74 | SLC2A1 (0.66) | PIM1ENPP2PPARGPTPN1ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973062-B2 | Androgen receptor-ablative agents | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-07-05 | — | — | US | disclosed |