Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12407262 | 0.93 | PTGER1 (0.62) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12407148 | 0.93 | PTGER1 (0.62) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12481949 | 0.90 | PTGER1 (0.70) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12407227 | 0.89 | PTGER1 (0.58) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12407221 | 0.87 | PTGER1 (0.61) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12482227 | 0.87 | PTGER1 (0.70) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12407445 | 0.86 | PTGER1 (0.82) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12407153 | 0.86 | PTGER1 (0.54) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12407152 | 0.86 | PTGER1 (0.54) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12407228 | 0.86 | PTGER1 (0.59) | PTGER1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050446-B1 | SULFONAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-7973078-B2 | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20090312328-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312328-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | PTGER1, CYSLTR1, PTGER2 | PTGER1 1/4885MAPT 4297/4885MEN1 3347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.