SCHEMBL1241035

SCHEMBL1241035

CC1=Cc2ccccc2C1C[SiH2]CC1C(C)=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
NFKB1 P19838 1/20 0.35
CHRM3 P20309 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
THPO P40225 1/20 0.35
OPRK1 P41145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4006186 0.98 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL1453437 0.82 HTR2A (0.42) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL1452870 0.82 HTR2A (0.42) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL4005225 0.80 HTR2A (0.41) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6238627 0.80 HTR2A (0.41) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7105374 0.78 HTR2A (0.47) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL8679551 0.78 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6240159 0.78 HTR2A (0.36) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7783135 0.77 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL28735635 0.76 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2307466-B1 CATALYST SYSTEM AND PROCESS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2015-05-20 EP claimed
EP-1994065-A1 PROCESS FOR PRODUCING PROPYLENE COPOLYMERS Exxonmobil Chemical Patents Inc. (US) 2008-11-26 EP claimed
WO-2007106238-A1 PROCESS FOR PRODUCING PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-09-20 WO claimed
WO-2005003184-A1 POLYMERIZATION PROCESSES USING ANTISTATIC AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-13 WO claimed
EP-0870779-B1 Metallocene catalyst and catalyst system for producing polypropylene blend of iso- and syndiotactic polypropylene. FINA TECHNOLOGY (US) 2005-01-12 EP claimed
EP-1287009-B1 ENHANCED SYNTHESIS OF RACEMIC METALLOCENES ALBEMARLE CORP (US) 2004-02-04 EP claimed
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed
EP-1287009-A1 ENHANCED SYNTHESIS OF RACEMIC METALLOCENES ALBEMARLE CORPORATION (US) 2003-03-05 EP claimed
WO-2001094360-A1 ENHANCED SYNTHESIS OF RACEMIC METALLOCENES ALBEMARLE CORPORATION (US) 2001-12-13 WO claimed
WO-2001053356-A1 CATALYST SYSTEM WITH A SELECTED TRANSITION METAL: COCATALYST RATIO BASELL POLYOLEFINE GMBH (DE) 2001-07-26 WO claimed
US-6252098-B1 Enhanced synthesis of racemic metallocenes ALBEMARLE CORPORATION 2001-06-26 US claimed
US-6239060-B1 Supported metallocene catalyst system and method for polymerizing olefins PHILLIPS PETROLEUM COMPANY 2001-05-29 US claimed
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US claimed
EP-0822938-B1 ENHANCED SYNTHESIS OF RACEMIC METALLOCENES ALBEMARLE CORP (US) 1999-06-16 EP claimed
US-5883278-A Enhanced synthesis of racemic metallocenes ALBEMARLE CORPORATION (US) 1999-03-16 US claimed
EP-0870779-A1 Metallocene catalyst and catalyst system for producing polypropylene blend of iso- and syndiotactic polypropylene. FINA TECHNOLOGY, INC. (US) 1998-10-14 EP claimed
US-5556997-A Enhanced synthesis of racemic metallocenes ALBEMARLE CORPORATION (US) 1996-09-17 US claimed
WO-2023085817-A1 METALLOCENE COMPOUND FOR POLYMERIZATION OF ULTRA-HIGH MOLECULAR WEIGHT POLYOLEFIN, AND METHOD FOR PREPARING ULTRA-HIGH MOLECULAR WEIGHT POLYOLEFIN POLYMER USING SAME 주식회사 에스피씨아이 2023-05-19 WO disclosed
WO-1994028034-A1 SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF EXXON CHEMICAL PATENTS INC. (US) 1994-12-08 WO disclosed
EP-0593888-A1 Polyolefin composition for injection moulding of transparent articles with high rigidity HOECHST AKTIENGESELLSCHAFT (DE) 1994-04-27 EP disclosed