⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21381116 | 1.00 | — | — | |
| SCHEMBL16538593 | 0.86 | KDM4E (0.31) | — | |
| SCHEMBL16538812 | 0.86 | KDM4E (0.31) | — | |
| SCHEMBL18112524 | 0.80 | GRIN2B (0.31) | — | |
| SCHEMBL143673 | 0.79 | KMT2A (0.39) | — | |
| SCHEMBL3981081 | 0.79 | KMT2A (0.39) | — | |
| SCHEMBL28433251 | 0.79 | GAA (0.41) | — | |
| SCHEMBL3476105 | 0.78 | — | — | |
| SCHEMBL3476103 | 0.78 | — | — | |
| SCHEMBL140892 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11111237-B2 | Bicyclic compound and use thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2021-09-07 | — | — | US | disclosed |
| US-20210101892-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. | 2021-04-08 | — | — | US | disclosed |
| US-20110263561-A1 | Novel pyrrolidone derivatives for use as MetAP-2 inhibitors | MERCK PATENT GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
| WO-2011016234-A1 | PICOLINAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2011-02-10 | — | — | WO | disclosed |