Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 17/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12702983 | 1.00 | BCHE (0.59) | BCHEHSP90AA1PTPN1MAPT | |
| SCHEMBL12942000 | 1.00 | BCHE (0.59) | BCHEHSP90AA1PTPN1MAPT | |
| SCHEMBL12411490 | 1.00 | BCHE (0.59) | BCHEHSP90AA1PTPN1MAPT | |
| SCHEMBL19178469 | 0.94 | BCHE (0.57) | BCHEPTPN1MAPT | |
| SCHEMBL13367641 | 0.92 | BCHE (0.66) | BCHEHSP90AA1PTPN1 | |
| SCHEMBL12702984 | 0.92 | BCHE (0.66) | BCHEHSP90AA1PTPN1 | |
| SCHEMBL12411417 | 0.92 | BCHE (0.66) | BCHEHSP90AA1PTPN1 | |
| SCHEMBL7530640 | 0.92 | BCHE (0.66) | BCHEHSP90AA1PTPN1 | |
| SCHEMBL9946847 | 0.92 | BCHE (0.66) | BCHEHSP90AA1PTPN1 | |
| SCHEMBL18306889 | 0.92 | BCHE (0.66) | BCHEHSP90AA1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334393-B2 | Chiral compounds and liquid crystal compositions and polymer networks derived therefrom | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-18 | — | — | US | disclosed |
| US-20110163267-A1 | CHIRAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-07 | — | — | US | disclosed |
| US-7914700-B2 | Liquid crystal compositions and polymer networks derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7914700-B2 | Liquid crystal compositions and polymer networks derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| US-20070267599-A1 | Liquid crystal compositions and polymer networks derived therefrom | GOLDFINGER MARC B | 2007-11-22 | — | — | US | disclosed |
| US-20070267599-A1 | Liquid crystal compositions and polymer networks derived therefrom | GOLDFINGER MARC B | 2007-11-22 | — | — | US | disclosed |
| WO-2007120459-A2 | CHIRAL DIOLE COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070267599-A1 | Liquid crystal compositions and polymer networks derived therefrom | F2, CCNB1, CYP2F1 | BCHE 4080/4885HSP90AA1 4770/4885PTPN1 1979/4885 |
| US-20110163267-A1 | CHIRAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | CCNB1, F2, CYP4F11 | BCHE 3686/4885HSP90AA1 4811/4885PTPN1 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.