Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 1.00 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SHBG | P04278 | 4/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14871417 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL11627782 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL16387354 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL20088312 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL868884 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL17591556 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL17831183 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL11632217 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL21807725 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL30875868 | 1.00 | CYP19A1 (1.00) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994402-B2 | Method of increasing plant organ and seed size in a plant | MONSANTO TECHNOLOGY LLC (US) | 2011-08-09 | — | — | US | disclosed |
| WO-2009074313-A1 | METHOD FOR THE AROMATIZATION OF 19-NOR-ANDROST-4-EN-3-ONES INTO ESTRA-1,3,5(10)-TRIENES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | disclosed |
| US-20090156843-A1 | PROCESS FOR AROMATIZING 19-NORANDROST-4-EN-3-ONES TO ESTRA-1,3,5(10)-TRIENES | BAYER SCHERING PHARMA AG (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20090156843-A1 | PROCESS FOR AROMATIZING 19-NORANDROST-4-EN-3-ONES TO ESTRA-1,3,5(10)-TRIENES | BAYER SCHERING PHARMA AG (DE) | 2009-06-18 | — | — | US | disclosed |
| EP-2070942-A1 | Method for aromatising 19-nor-androst-4-en-3-ones to estra-1,3,5(10)-trienes | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |
| US-20090133162-A1 | Method of increasing plant organ and seed size in a plant | FERNANDES MARY | 2009-05-21 | — | — | US | disclosed |
| EP-1226155-B1 | 18-NOR-STEROIDS AS SELECTIVELY ACTIVE ESTROGENS | BAYER SCHERING PHARMA AG (DE) | 2007-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156843-A1 | PROCESS FOR AROMATIZING 19-NORANDROST-4-EN-3-ONES TO ESTRA-1,3,5(10)-TRIENES | CYP19A1, HSD17B11, NR5A1 | CYP19A1 1/4885SERPINA6 991/4885ALDH1A1 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.