Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12414745 | 0.92 | ANPEP (0.35) | ANPEPDPP4NR1H2NR1H3ADRB2 | |
| SCHEMBL12414732 | 0.91 | ANPEP (0.39) | ANPEPDPP4NR1H2NR1H3 | |
| SCHEMBL12414728 | 0.91 | MCL1 (0.33) | ANPEPDPP4 | |
| SCHEMBL13521562 | 0.89 | ANPEP (0.36) | ANPEPDPP4 | |
| SCHEMBL12414744 | 0.89 | ANPEP (0.36) | ANPEPDPP4PPARG | |
| SCHEMBL12414748 | 0.89 | ANPEP (0.37) | ANPEPDPP4NR1H2NR1H3BCL2L2 | |
| SCHEMBL13532263 | 0.89 | ANPEP (0.33) | ANPEPDPP4 | |
| SCHEMBL12414742 | 0.85 | KDM4E (0.33) | ANPEPDPP4ADRB2ADRB1ADRB3 | |
| SCHEMBL24012109 | 0.84 | ANPEP (0.45) | ANPEPDPP4NR1H2NR1H3 | |
| SCHEMBL14309158 | 0.83 | ANPEP (0.43) | ANPEPDPP4NR1H2NR1H3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921558-B2 | Azide substituted naphthylene or rylene imide derivatives and their use as reagents in click-reactions | BASF SE (DE) | 2014-12-30 | — | — | US | disclosed |
| US-8802852-B2 | Azide substituted naphthylene or rylene imide derivatives and their use as reagents in click-reactions | BASF SE (DE) | 2014-08-12 | — | — | US | disclosed |
| US-20140080220-A1 | Azide Substituted Naphthylene or Rylene Imide Derivatives and their Use as Reagents in Click-Reactions | BASF SE (DE) | 2014-03-20 | — | — | US | disclosed |
| US-20140073059-A1 | Azide Substituted Naphthylene or Rylene Imide Derivatives and their Use as Reagents in Click-Reactions | BASF SE (DE) | 2014-03-13 | — | — | US | disclosed |
| US-20110165691-A1 | AZIDE SUBSTITUTED NAPHTHYLENE OR RYLENE IMIDE DERIVATIVES AND THEIR USE AS REAGENTS IN CLICK-REACTIONS | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080220-A1 | Azide Substituted Naphthylene or Rylene Imide Derivatives and their Use as Reagents in Click-Reactions | NANS, NANP, GNE | ANPEP 119/4885DPP4 1737/4885NR1H2 4617/4885 |
| US-20110165691-A1 | AZIDE SUBSTITUTED NAPHTHYLENE OR RYLENE IMIDE DERIVATIVES AND THEIR USE AS REAGENTS IN CLICK-REACTIONS | NANS, NANP, GNE | ANPEP 119/4885DPP4 1737/4885NR1H2 4617/4885 |
| US-20140073059-A1 | Azide Substituted Naphthylene or Rylene Imide Derivatives and their Use as Reagents in Click-Reactions | NANS, NANP, GNE | ANPEP 119/4885DPP4 1737/4885NR1H2 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.