⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26323784 | 0.82 | — | — | |
| SCHEMBL26323781 | 0.77 | — | — | |
| SCHEMBL24032977 | 0.64 | — | — | |
| SCHEMBL27428514 | 0.63 | — | — | |
| SCHEMBL17914105 | 0.62 | POLB (0.33) | — | |
| SCHEMBL26031122 | 0.61 | — | — | |
| SCHEMBL24037480 | 0.61 | — | — | |
| SCHEMBL26323877 | 0.59 | — | — | |
| SCHEMBL17124623 | 0.59 | — | — | |
| SCHEMBL17124624 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327824-A1 | SELECTIVE ANTISENSE COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2017-11-16 | — | — | US | disclosed |
| US-9409934-B2 | Cyclohexenyl nucleic acids analogs | IONIS PHARMACEUTICALS, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150275208-A1 | SELECTIVE ANTISENSE COMPOUNDS AND USES THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 2015-10-01 | — | — | US | disclosed |
| US-20140073786-A1 | CYCLOHEXENYL NUCLEIC ACIDS ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-20110172294-A1 | CYCLOHEXENYL NUCLEIC ACIDS ANALOGS | IONIS PHARMACEUTICALS, INC. | 2011-07-14 | — | — | US | disclosed |