Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277884 | 0.96 | POLB (0.33) | POLBHSD17B10 | |
| SCHEMBL12973764 | 0.91 | POLB (0.31) | POLBHSD17B10 | |
| SCHEMBL13339558 | 0.88 | POLB (0.33) | POLBHSD17B10 | |
| SCHEMBL277693 | 0.87 | SMN1; SMN2 (0.36) | POLBHSD17B10 | |
| SCHEMBL16441085 | 0.87 | — | — | |
| SCHEMBL15144368 | 0.86 | SMN1; SMN2 (0.38) | POLBHSD17B10 | |
| SCHEMBL15381133 | 0.86 | FOLH1 (0.32) | — | |
| SCHEMBL12410281 | 0.84 | POLB (0.32) | POLBHSD17B10 | |
| SCHEMBL12410650 | 0.83 | POLB (0.30) | POLBHSD17B10 | |
| SCHEMBL277686 | 0.82 | SMN1; SMN2 (0.39) | POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171162-A1 | POLYMER CONJUGATES OF THYMOSIN ALPHA 1 PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171162-A1 | POLYMER CONJUGATES OF THYMOSIN ALPHA 1 PEPTIDES | TMSB4X, TMSB10, TAP1 | POLB 2957/4885HSD17B10 3960/4885DRD2 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.