SCHEMBL12417486

SCHEMBL12417486

O=[N+]([O-])c1ccc(NC2C(O)[C@@H](O)C(CO)O[C@H]2O)c2nonc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 1/20 0.51
GSTM2 P28161 1/20 0.49
GRK6 P43250 2/20 0.47
MEN1 O00255 7/20 0.46
KMT2A Q03164 7/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
USP2 O75604 1/20 0.46
HTT P42858 1/20 0.46
RECQL P46063 1/20 0.46
MYC P01106 4/20 0.46
IDO1 P14902 3/20 0.46
HK1 P19367 1/20 0.45
HK2 P52789 1/20 0.45
MAX P61244 1/20 0.44
MIF P14174 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34510 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL14639838 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL15763297 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL15494585 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL29402554 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL15765529 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL14440339 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL12417485 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL15763307 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A
SCHEMBL15763313 1.00 SLC5A2 (0.51) SLC5A2GSTM2GRK6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110189708-A1 METHOD FOR EVALUATING SPECIFIC INCORPORATION OF D-GLUCOSE INTO CELLS HIROSAKI UNIVERSITY (JP) 2011-08-04 US disclosed
EP-2325327-A1 METHOD FOR EVALUATING SPECIFIC INCORPORATION OF D-GLUCOSE INTO CELLS Hirosaki University (JP) 2011-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110189708-A1 METHOD FOR EVALUATING SPECIFIC INCORPORATION OF D-GLUCOSE INTO CELLS SLC2A4, SLC2A3, SLC2A1 SLC5A2 6/4885GSTM2 3605/4885GRK6 2765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.