Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375140 | 0.82 | CDK1 (0.57) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL4572145 | 0.80 | ADORA2A (0.56) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL24954186 | 0.80 | CDK1 (0.46) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL31106979 | 0.80 | CDK1 (0.46) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL19779231 | 0.80 | PI4KA (0.54) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL12379216 | 0.80 | CDK1 (0.65) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL14401041 | 0.80 | CDK1 (0.65) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL19760046 | 0.77 | CDK1 (0.50) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL19618133 | 0.77 | CDK1 (0.50) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL129642 | 0.77 | CDK1 (0.68) | CDK1ADORA2AADORA1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | CDK1 2791/4885ADORA2A 2428/4885ADORA1 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.