SCHEMBL124179

SCHEMBL124179

CC(=O)NC(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6363154 1.00
Lithium SCHEMBL669188 0.97
Hydrochloric Acid SCHEMBL30777463 0.97
SCHEMBL11764059 0.91 EPHX1 (0.48)
SCHEMBL28581256 0.86 EPHX1 (0.44)
Trifluoroacetic Acid SCHEMBL30076041 0.84 EPHX1 (0.43)
Propane SCHEMBL10617202 0.78 EPHX1 (0.43)
SCHEMBL30516878 0.78
SCHEMBL9913287 0.76 EPHX1 (0.40)
SCHEMBL11123806 0.76 EPHX1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1804 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380998-A2 METHOD OF SYNTHESIZING A MUCIN AND PRODUCT THEREOF Research Foundation Of The City University Of New York (US) 2024-06-12 EP claimed
WO-2023014875-A2 METHOD OF SYNTHESIZING A MUCIN AND PRODUCT THEREOF RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2023-02-09 WO claimed
CN-114361494-A Composite bipolar plate and preparation method and application thereof 未势能源科技有限公司 2022-04-15 CN claimed
CN-106861696-B A kind of graphene-supported iron aluminium composite magnetic catalyst and its preparation method and application 浙江大学 2019-08-20 CN claimed
EP-2344456-B1 NOVEL POTASSIUM CHANNEL BLOCKER JAPAN TOBACCO INC (JP) 2018-07-25 EP claimed
US-9896668-B2 Substrate-mimetic AKT inhibitor UNIVERSITY OF SOUTH FLORIDA (US) 2018-02-20 US claimed
EP-2928867-B1 PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS HOFFMANN LA ROCHE (CH) 2017-08-09 EP claimed
EP-2928868-B1 PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS HOFFMANN LA ROCHE (CH) 2017-08-09 EP claimed
EP-2334637-B1 NOVEL POTASSIUM CHANNEL BLOCKERS JAPAN TOBACCO INC (JP) 2017-01-04 EP claimed
US-20160369247-A1 SUBSTRATE-MIMETIC AKT INHIBITOR UNIVERSITY OF SOUTH FLORIDA (US) 2016-12-22 US claimed
US-6458779-B1 TREATMENT OF CONDITIONS ASSOCIATED WITH EXCESS PRODUCTION OF SOLUBLE CD23 (S-CD23) SUCH AS AUTOIMMUNE DISEASE AND ALLERGY. THE COMPOUNDS OF THE INVENTION ARE ALSO INHIBITORS OF THE RELEASE OF TUMOUR NECROSIS FACTOR (TNF). SMITHKLINE BEECHAM P.L.C. (GB) 2002-10-01 US claimed
WO-2002000644-A1 GUANIDINE DERIVATIVES OF QUINAZOLINE AND QUINOLINE FOR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES ASTRAZENECA AB (SE) 2002-01-03 WO claimed
EP-0748802-B1 Process for the preparation of alpha-methyl-2-thiopheneacetic acid derivatives ERREGIERRE SPA (IT) 2001-03-28 EP claimed
US-5650522-A MULTISTAGE PROCESS TO FORM KETONE, THEN REACTION WITH HALODIESTER COMPOUND TO FORM KETOTHIOPHENEDIESTER THEN SAPONIFICATION WITH ALKALI AND MINERAL ACID ERREGIERRE S.P.A. (IT) 1997-07-22 US claimed
EP-0748802-A1 Process for the preparation of alpha-methyl-2-thiopheneacetic acid derivatives ERREGIERRE S.p.A. (IT) 1996-12-18 EP claimed
US-5476743-A Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant XEROX CORPORATION (US) 1995-12-19 US claimed
CN-1062536-A Retroviral protease inhibitors from 3-chloro-2-chloromethyl-1-propylene derived AMERICAN CYANAMID CO (US) 1992-07-08 CN claimed
EP-0492136-A2 Retroviral protease inhibitors derived from 3-chloro-2-chloromethyl-1-propene AMERICAN CYANAMID COMPANY (US) 1992-07-01 EP claimed
US-5103055-A Water-promoted synthesis of amides from nitriles and alcohols THE STANDARD OIL COMPANY (US) 1992-04-07 US claimed
US-4123607-A BACTERICIDES AMERICAN CYANAMID COMPANY (US) 1978-10-31 US claimed