SCHEMBL124185

SCHEMBL124185

[CH2]/C(C)=C\C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18791 1.00
SCHEMBL19441 1.00
SCHEMBL28211829 0.95
SCHEMBL587713 0.74
SCHEMBL587712 0.74
SCHEMBL6860403 0.74
SCHEMBL84212 0.74
SCHEMBL687113 0.74
SCHEMBL5987884 0.71
SCHEMBL8309593 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 918 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677443-B Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation 中国科学院理化技术研究所 2024-07-16 CN disclosed
US-20240228501-A1 IMIDAZOLE-CONTAINING CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US disclosed
CN-115232184-B Ribofuranosylpyridine derivatives, pharmaceutical compositions and uses thereof 宁波熙健医药科技有限公司 2024-07-05 CN disclosed
CN-117362493-B Catalytic system for olefin polymerization and application thereof 辽宁格瑞斯化工有限公司 2024-07-05 CN disclosed
WO-2024140933-A1 CAMPTOTHECIN DERIVATIVE, PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD AND USE THEREFOR 长春金赛药业有限责任公司 2024-07-04 WO disclosed
WO-2024140824-A1 PYRIDAZINE NLRP3 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 长春金赛药业有限责任公司 2024-07-04 WO disclosed
WO-2024140736-A1 TRIPEPTIDE EPOXY KETONE COMPOUND, PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海美悦生物科技发展有限公司 2024-07-04 WO disclosed
CN-118271467-A Alcohol-plastic polysaccharide derivative and preparation method and application thereof 中国科学院化学研究所 2024-07-02 CN disclosed
CN-118255835-A Tripeptide epoxy ketone compound, pharmaceutical composition, preparation method and application thereof 上海美悦生物科技发展有限公司 2024-06-28 CN disclosed
CN-113348165-B 1,2, 4-Triazin-3 (2H) -one compounds for the treatment of hyperproliferative diseases 拜耳股份有限公司 2024-06-25 CN disclosed
WO-2006099974-A1 N-ARYL-SULFOXIMINE-SUBSTITUTED PYRIMIDINES AS CDK- AND/OR VEGF INHIBITORS, THEIR PRODUCTION AND USE AS PHARMACEUTICAL AGENTS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
US-7074798-B2 Xanthine derivative and DPPIV inhibitor EISAI CO., LTD (JP) 2006-07-11 US disclosed
US-20060116406-A1 7-(1,3-thiazol-2-yl)thio!-coumarin derivatives and their use as leukotriene biosynthesis inhibitors GAREAU YVES 2006-06-01 US disclosed
EP-1622924-A2 8$G(B)-VINYL-11$G(B)-( G(V)-SUBSTITUTED)ALKYL-ESTRA-1,3,5(10)-TRIENES Schering Aktiengesellschaft (DE) 2006-02-08 EP disclosed
US-20050065135-A1 8beta-Vinyl-11beta-(omega-substituted)alkyl-estra-1,3,5(10)-trienes BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-03-24 US disclosed
US-6861432-B2 Piperazine derivatives that destabilize androgen receptors SCHERING AKTIENGESELLSCHAFT (DE) 2005-03-01 US disclosed
WO-2004094451-A2 8&amp;dollar;G(B)-VINYL-11&amp;dollar;G(B)-(&amp;dollar;G(V)-SUBSTITUTED)ALKYL-ESTRA-1,3,5(10)-TRIENES SCHERING AKTIENGESELLSCHAFT (DE) 2004-11-04 WO disclosed
US-20040082570-A1 Xanthine derivative and DPPIV inhibitor EISAI CO., LTD. (JP) 2004-04-29 US disclosed
US-20040009969-A1 Piperazine derivatives that destabilize androgen receptors SCHERING AG (DE) 2004-01-15 US disclosed
EP-1338595-A2 Xanthine derivatives as DPP-IV inhibitors Eisai Co., Ltd. (JP) 2003-08-27 EP disclosed