2-Methylindole

2-Methylindole

SCHEMBL12420

Cc1cc2ccccc2[nH]1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.57
AOC3 Q16853 2/20 0.54
CYP2A6 P11509 2/20 0.54
KEAP1 Q14145 1/20 0.54
KDM4E B2RXH2 4/20 0.52
GAA P10253 3/20 0.52
CYP1A2 P05177 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52
AURKA O14965 1/20 0.52
AURKB Q96GD4 1/20 0.52
AXL P30530 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.48
FLT3 P36888 1/20 0.48
MAPT P10636 3/20 0.47
ALDH1A1 P00352 2/20 0.47
DAO P14920 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Methylindole SCHEMBL29377448 1.00 BRD4 (0.57) BRD4AOC3CYP2A6KEAP1KDM4E
2-Methylindole SCHEMBL28876208 0.98 BRD4 (0.55) BRD4AOC3CYP2A6KEAP1KDM4E
SCHEMBL21284843 0.98 BRD4 (0.55) BRD4AOC3CYP2A6KEAP1KDM4E
2-Methylindole SCHEMBL27901243 0.98 AOC3 (0.56) BRD4AOC3CYP2A6KEAP1KDM4E
2-Methylindole SCHEMBL29226785 0.98 BRD4 (0.55) BRD4AOC3CYP2A6KEAP1KDM4E
2-Methylindole SCHEMBL6480418 0.98 BRD4 (0.55) BRD4AOC3CYP2A6KEAP1KDM4E
2-Methylindole SCHEMBL28806610 0.98 BRD4 (0.55) BRD4AOC3CYP2A6KEAP1KDM4E
2-Methylindole SCHEMBL31025706 0.98 BRD4 (0.55) BRD4AOC3CYP2A6KEAP1KDM4E
2-Methylindole SCHEMBL28273394 0.95 BRD4 (0.53) BRD4AOC3CYP2A6KEAP1KDM4E
2-Methylindole SCHEMBL27523440 0.95 BRD4 (0.53) BRD4AOC3CYP2A6KEAP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6904 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112021315-B Method for killing bacteria for non-therapeutic purpose 福建师范大学 2026-05-22 CN claimed
CN-118005569-B 6-Aminoquinoxaline compound and preparation method and application thereof 华南理工大学 2026-05-19 CN claimed
CN-118755083-B Bio-based polyamide polyester, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-12 CN claimed
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US claimed
EP-3969457-B1 METHODS OF PREPARING MACROCYCLIC INDOLES BROAD INST INC (US) 2025-08-13 EP claimed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US claimed
US-12338250-B2 Methods of preparing macrocyclic indoles THE BROAD INSTITUTE, INC. (US) 2025-06-24 US claimed
CN-119733561-B Use of lithium magnesium nitrogen hydrogen material 有研(广东)新材料技术研究院 2025-06-13 CN claimed
CN-116103191-B Bacillus subtilis JN-K1 and application thereof in sewage treatment 山东劲牛集团股份有限公司 2025-04-01 CN claimed
CN-119733561-A Use of lithium magnesium nitrogen hydrogen material 有研(广东)新材料技术研究院 2025-04-01 CN claimed
EP-0042357-A2 Azo dyes, their preparation and use CIBA-GEIGY AG (CH) 1981-12-23 EP claimed
EP-0039306-A1 Azo dyestuffs, methods for their preparation and their use CIBA-GEIGY AG (CH) 1981-11-04 EP claimed
US-4298741-A DETHIAPENICILLIN ANTIBIOTICS MERCK & CO., INC. (US) 1981-11-03 US claimed
US-4297488-A 7-α-Methoxy cephalosporins MERCK & CO., INC. (US) 1981-10-27 US claimed
US-4258040-A Cephalosporin compounds MERCK & CO., INC. (US) 1981-03-24 US claimed
US-4245995-A Stabilization of anionic indole dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US claimed
US-4094676-A Non-silver salt type photosensitive composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-06-13 US claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-4060687-A Cephalosporins having a 3-α substituted alkyl grouping MERCK & CO., INC. (US) 1977-11-29 US claimed
US-4022802-A INDOLES, ALKALI HYDROXIDE; ALKYLATION CIBA-GEIGY AG (CH) 1977-05-10 US claimed