Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 14/20 | 0.56 |
| ▸ | XIAP | P98170 | 13/20 | 0.56 |
| ▸ | BIRC3 | Q13489 | 9/20 | 0.56 |
| ▸ | BIRC7 | Q96CA5 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104608 | 0.95 | XIAP (0.58) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL14288620 | 0.95 | XIAP (0.58) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL10081803 | 0.95 | XIAP (0.58) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL12381376 | 0.94 | XIAP (0.56) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL10082402 | 0.93 | BIRC2 (0.58) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL13104606 | 0.93 | BIRC2 (0.58) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL10081738 | 0.93 | XIAP (0.59) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL10082026 | 0.92 | XIAP (0.58) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL1273401 | 0.91 | XIAP (0.68) | BIRC2XIAPBIRC3BIRC7 | |
| SCHEMBL10066036 | 0.91 | XIAP (0.60) | BIRC2XIAPBIRC3BIRC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551955-B2 | Dimeric Smac mimetics | JOYANT PHARMACEUTICALS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20110195043-A1 | Dimeric Smac Mimetics | JOYANT PHARMACEUTICALS, INC. | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195043-A1 | Dimeric Smac Mimetics | BID, BIRC2, BAD | BIRC2 2/4885XIAP 19/4885BIRC3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.