SCHEMBL12423311

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12423256	0.93	AKT3 (0.52)	ROCK1AKT3CNR2PIK3CGGSK3B
	SCHEMBL12423308	0.90	AKT3 (0.54)	AKT3SYKIKBKBCAMK2D
	SCHEMBL12423258	0.90	AKT3 (0.49)	AKT3CDK1CDK2DYRK1A
	SCHEMBL12423375	0.90	AKT3 (0.49)	AKT3PIK3CGPIK3CAPIK3CBSYK
	SCHEMBL14100381	0.89	AKT3 (0.55)	ROCK1AKT3CNR2PIK3CGGSK3B
	SCHEMBL12423346	0.89	AKT3 (0.49)	AKT3CNR2SYKIKBKBMAPK1
	SCHEMBL4919836	0.88	AKT3 (0.52)	ROCK1AKT3CNR2PIK3CGPIK3CA
	SCHEMBL13154120	0.87	AKT3 (0.50)	AKT3IKBKBCDK2CAMK2D
	SCHEMBL13154135	0.87	AKT3 (0.54)	AKT3AURKAAURKBCDK1CDK2
	SCHEMBL2198523	0.87	AKT3 (0.47)	AKT3IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.