Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238048 | 1.00 | CETP (0.45) | CETPADORA3 | |
| SCHEMBL16258381 | 0.91 | CETP (0.46) | CETPADORA3 | |
| SCHEMBL10196401 | 0.89 | CETP (0.42) | CETP | |
| SCHEMBL12423436 | 0.89 | CETP (0.42) | CETP | |
| SCHEMBL10238087 | 0.85 | CETP (0.36) | CETP | |
| SCHEMBL662322 | 0.85 | CETP (0.48) | CETP | |
| SCHEMBL665049 | 0.82 | CYP1A2 (0.36) | CETPADORA3 | |
| SCHEMBL12423601 | 0.81 | CETP (0.48) | CETPADORA3 | |
| SCHEMBL10196402 | 0.81 | CETP (0.51) | CETPADORA3 | |
| SCHEMBL10196407 | 0.81 | CETP (0.48) | CETPADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536733-B1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INT (DE) | 2014-11-26 | — | — | EP | disclosed |
| WO-2011101424-A1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-25 | — | — | WO | disclosed |