SCHEMBL12424909

SCHEMBL12424909

O=C1NC(c2c(Cl)cccc2Cl)=C2C(=O)NC(c3c(Cl)cccc3Cl)=C12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.52
RET P07949 1/20 0.44
GRK5 P34947 1/20 0.44
TYRO3 Q06418 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
NSD2 O96028 1/20 0.42
BCHE P06276 1/20 0.42
DAO P14920 1/20 0.42
STK10 O94804 6/20 0.42
SLK Q9H2G2 6/20 0.42
GSK3B P49841 4/20 0.42
TGM2 P21980 2/20 0.40
PBRM1 Q86U86 4/20 0.39
GRIA1 P42261 1/20 0.38
CACNG8 Q8WXS5 1/20 0.38
GSK3A P49840 1/20 0.37
AHR P35869 1/20 0.37
SMARCA2 P51531 1/20 0.37
SMARCA4 P51532 1/20 0.37
HTR2A P28223 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425026 0.87 PBRM1 (0.45) CES1RETGRK5TYRO3DYRK1B
SCHEMBL12424901 0.82 GRIA1 (0.49) CES1STK10SLKGSK3BTGM2
SCHEMBL30445783 0.82 CES1 (0.55) CES1RETGRK5TYRO3DYRK1B
SCHEMBL12424922 0.81 GSK3B (0.45) CES1GSK3BGSK3A
SCHEMBL12425035 0.79 PBRM1 (0.41) CES1STK10SLKGSK3BPBRM1
SCHEMBL12424905 0.78 CES1 (0.52) CES1NSD2BCHEDAOSTK10
SCHEMBL9340330 0.77 STK10 (0.57) CES1NSD2BCHEDAOSTK10
SCHEMBL2834495 0.77 CES1 (0.50) CES1RETGRK5TYRO3DYRK1B
SCHEMBL12424890 0.75 CES1 (0.44) CES1NSD2BCHEDAOSTK10
SCHEMBL12425023 0.74 CA9 (0.41) CES1DAOSTK10SLKPBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed