Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381390 | 0.92 | HPGD (0.50) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12425674 | 0.86 | MEN1 (0.52) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1966330 | 0.82 | KDM4E (0.40) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1967869 | 0.82 | HPGD (0.58) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1968392 | 0.79 | MEN1 (0.50) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1488845 | 0.75 | HPGD (0.40) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL30904986 | 0.75 | KDM4E (0.59) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL30096226 | 0.74 | KDM4E (0.46) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL9699117 | 0.73 | KDM4E (0.51) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12425519 | 0.72 | CSNK2A2 (0.51) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110200557-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110200557-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | S1PR2, S1PR3, S1PR1 | KDM4E 4607/4885HPGD 1378/4885ALDH1A1 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.