Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158616 | 0.92 | HPGD (0.46) | HPGDUSP2CYP2D6CYP2C19MMP1 | |
| SCHEMBL24778821 | 0.80 | HPGD (0.50) | HPGDUSP2CYP2D6CYP2C19MMP1 | |
| SCHEMBL19879078 | 0.78 | CYP2D6 (0.46) | HPGDUSP2CYP2D6CYP2C19MMP1 | |
| SCHEMBL10447542 | 0.78 | CYP2D6 (0.62) | HPGDUSP2CYP2D6CYP2C19MMP1 | |
| SCHEMBL24330217 | 0.75 | GAA (0.39) | HPGDSMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL24474417 | 0.75 | HPGD (0.50) | HPGDUSP2CYP2D6CYP2C19MMP1 | |
| SCHEMBL15099963 | 0.74 | MAPT (0.36) | SMN1; SMN2LMNAKDM4ERECQLMAPT | |
| SCHEMBL20987826 | 0.74 | HPGD (0.45) | HPGDUSP2CYP2D6CYP2C19MMP1 | |
| SCHEMBL6644938 | 0.73 | CYP2D6 (0.56) | HPGDUSP2CYP2D6CYP2C19MMP1 | |
| SCHEMBL11919895 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580211-B1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-19 | — | — | EP | disclosed |
| EP-2536698-B1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-10 | — | — | EP | disclosed |
| WO-2011154555-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011101402-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-25 | — | — | WO | disclosed |