SCHEMBL12425832

SCHEMBL12425832

COCOc1cc(Cl)c(Cc2cc3ccccc3s2)cc1[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 13/20 0.43
SLC5A1 P13866 7/20 0.43
BCHE P06276 1/20 0.35
SSTR1 P30872 1/20 0.34
SSTR2 P30874 1/20 0.34
SSTR4 P31391 1/20 0.34
SSTR3 P32745 1/20 0.34
SSTR5 P35346 1/20 0.34
PDE2A O00408 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425873 0.93 SLC5A2 (0.38) SLC5A2SLC5A1BCHESSTR1SSTR2
SCHEMBL12425887 0.92 SLC5A2 (0.51) SLC5A2SLC5A1BCHESSTR1SSTR2
SCHEMBL12425895 0.90 SLC5A2 (0.43) SLC5A2SLC5A1BCHE
SCHEMBL12425941 0.89 SLC5A2 (0.43) SLC5A2SLC5A1BCHE
SCHEMBL14453019 0.89 SLC5A2 (0.40) SLC5A2SLC5A1SSTR1SSTR2SSTR4
SCHEMBL12425872 0.87 SLC5A2 (0.48) SLC5A2BCHESSTR1SSTR2SSTR4
SCHEMBL14544795 0.87 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL12425882 0.86 SLC5A2 (0.49) SLC5A2SLC5A1BCHE
SCHEMBL12425957 0.85 SLC5A2 (0.47) SLC5A2SLC5A1BCHESSTR1SSTR2
SCHEMBL12425875 0.85 SLC5A2 (0.44) SLC5A2SLC5A1SSTR1SSTR2SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977466-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2011-07-12 US disclosed
US-7772407-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2010-08-10 US disclosed
US-20090069252-A1 C-GLYCOSIDE DERIVATIVES AND SALTS THEREOF ASTELLAS PHARMA INC. (JP) 2009-03-12 US disclosed
US-20070161787-A1 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-07-12 US disclosed
US-7202350-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161787-A1 C-glycoside derivatives and salts thereof SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885SLC5A1 1/4885BCHE 3240/4885
US-20090069252-A1 C-GLYCOSIDE DERIVATIVES AND SALTS THEREOF SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885SLC5A1 1/4885BCHE 3240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.