SCHEMBL12425890

SCHEMBL12425890

CC(C)(C)OC(=O)NCCOc1ccc(Cc2cc3ccccc3s2)cc1[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 4/20 0.41
PTPN1 P18031 6/20 0.40
CDC25B P30305 5/20 0.40
PTPN2 P17706 4/20 0.40
CDC25A P30304 3/20 0.40
PTPN6 P29350 1/20 0.40
PTPN11 Q06124 1/20 0.40
BCHE P06276 2/20 0.34
CNR2 P34972 1/20 0.34
TACR2 P21452 1/20 0.34
NT5E P21589 1/20 0.33
SSTR4 P31391 1/20 0.33
TACR1 P25103 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5520655 0.91 SLC5A2 (0.43) SLC5A2PTPN1CDC25BBCHETACR2
SCHEMBL12509830 0.90 SLC5A2 (0.42) SLC5A2PTPN1
SCHEMBL12425898 0.88 SLC5A2 (0.45) SLC5A2PTPN1BCHETACR2SSTR4
SCHEMBL5526843 0.87 PTPN1 (0.43) SLC5A2PTPN1CDC25BPTPN2CDC25A
SCHEMBL12425892 0.85 SLC5A2 (0.47) SLC5A2PTPN1CDC25BPTPN2PTPN6
SCHEMBL5531075 0.85 SLC5A2 (0.43) SLC5A2PTPN1CDC25BPTPN2PTPN6
SCHEMBL5526226 0.85 SLC5A2 (0.46) SLC5A2PTPN1CDC25BPTPN2PTPN6
SCHEMBL12425939 0.85 SLC5A2 (0.48) SLC5A2PTPN1CDC25BPTPN2PTPN6
SCHEMBL12425888 0.84 SLC5A2 (0.47) SLC5A2PTPN1PTPN2PTPN11TACR2
SCHEMBL5516727 0.83 SLC5A2 (0.45) SLC5A2PTPN1CDC25BPTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977466-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2011-07-12 US disclosed
US-7772407-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2010-08-10 US disclosed
US-20090069252-A1 C-GLYCOSIDE DERIVATIVES AND SALTS THEREOF ASTELLAS PHARMA INC. (JP) 2009-03-12 US disclosed
US-20070161787-A1 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-07-12 US disclosed
US-7202350-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161787-A1 C-glycoside derivatives and salts thereof SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885PTPN1 224/4885CDC25B 4395/4885
US-20090069252-A1 C-GLYCOSIDE DERIVATIVES AND SALTS THEREOF SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885PTPN1 224/4885CDC25B 4395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.