SCHEMBL12427437

SCHEMBL12427437

CCNC(=O)CC(F)(F)C(F)(F)OC(F)(F)C(C)(F)F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.32
FAAH O00519 1/20 0.32
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11996532 0.71 MCL1 (0.43) MCL1FAAHHDAC4HDAC1HDAC6
SCHEMBL1515360 0.68 HPGD (0.46) MCL1FAAHHDAC1HDAC6
SCHEMBL10293977 0.68
SCHEMBL21516603 0.66 PIK3CD (0.48) MCL1FAAHHDAC1HDAC6
SCHEMBL23505924 0.65 MCL1 (0.41) MCL1FAAH
SCHEMBL20290710 0.65 MCL1 (0.41) MCL1FAAH
SCHEMBL12464050 0.65 MCL1 (0.41) MCL1FAAHHDAC4HDAC1HDAC6
SCHEMBL22900019 0.65 MCL1 (0.41) MCL1FAAH
SCHEMBL1515359 0.65 MCL1 (0.41) MCL1FAAH
SCHEMBL22951039 0.64 MCL1 (0.38) MCL1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7976824-B2 Production of 2-18F-2-deoxy-D-glucose via solid-phase synthesis GE HEALTHCARE LIMITED (GB) 2011-07-12 US disclosed
US-20070274911-A1 Production of 2-18F-2-Deoxy-D-Glucose Via Solid-Phase Synthesis GE HEALTHCARE LIMITED (GB) 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070274911-A1 Production of 2-18F-2-Deoxy-D-Glucose Via Solid-Phase Synthesis SLC2A1, SLC2A4, SLC2A2 MCL1 2637/4885FAAH 4050/4885HDAC4 2754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.