Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM58 | Q8NG06 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2076699 | 0.89 | EGFR (0.34) | TRIM58EHMT2KDM1ARCOR1EHMT1 | |
| SCHEMBL2078688 | 0.84 | USP2 (0.34) | — | |
| SCHEMBL14206419 | 0.81 | BCDIN3D (0.32) | — | |
| SCHEMBL2078758 | 0.81 | EHMT2 (0.34) | EHMT2KDM1ARCOR1EHMT1 | |
| SCHEMBL2075562 | 0.80 | USP2 (0.35) | — | |
| SCHEMBL3773255 | 0.80 | USP2 (0.34) | — | |
| SCHEMBL2077706 | 0.80 | USP2 (0.35) | TRIM58EHMT2KDM1ARCOR1 | |
| SCHEMBL2076201 | 0.79 | EGFR (0.32) | EHMT2KDM1ARCOR1 | |
| Hydrochloric Acid SCHEMBL2078049 | 0.79 | USP2 (0.34) | — | |
| SCHEMBL2075420 | 0.79 | USP2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351751-A1 | Substituted pyrazolopyrimidines | CEPHALON, INC. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2008063232-A2 | SUBSTITUTED PYRAZOLOPYRIMIDINES | CEPHALON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |