Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 8/20 | 0.40 |
| ▸ | ABL1 | P00519 | 4/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 6/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.36 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | HCK | P08631 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.34 |
| ▸ | PRKDC | P78527 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301396 | 0.89 | PDE9A (0.41) | PDE9AABL1BCREGFRBTK | |
| SCHEMBL2075470 | 0.89 | PDE9A (0.40) | PDE9AABL1BCREGFRBTK | |
| SCHEMBL2077068 | 0.89 | PDE9A (0.40) | PDE9AABL1BCREGFRBTK | |
| SCHEMBL2075485 | 0.89 | PDE9A (0.51) | PDE9A | |
| SCHEMBL2075106 | 0.88 | PDE9A (0.41) | PDE9AABL1BCREGFRBTK | |
| SCHEMBL2077452 | 0.88 | PDE9A (0.52) | PDE9AABL1BCR | |
| SCHEMBL12427745 | 0.88 | PDE9A (0.41) | PDE9AABL1BCREGFRBTK | |
| SCHEMBL2078601 | 0.88 | PDE9A (0.41) | PDE9AABL1BCRBTKSLC2A1 | |
| SCHEMBL2078497 | 0.87 | PDE9A (0.48) | PDE9AABL1BCRSLC2A1SLC2A2 | |
| SCHEMBL2078197 | 0.87 | RET (0.43) | PDE9AABL1BCREGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351751-A1 | Substituted pyrazolopyrimidines | CEPHALON, INC. (US) | 2011-08-03 | — | — | EP | disclosed |