Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075420 | 0.89 | USP2 (0.35) | USP2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL3769627 | 0.88 | USP2 (0.35) | USP2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL2077881 | 0.87 | USP2 (0.35) | USP2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL2077027 | 0.87 | USP2 (0.35) | USP2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL2075562 | 0.87 | USP2 (0.35) | USP2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL2077029 | 0.87 | USP2 (0.35) | USP2ALDH1A1TP53MAPTLMNA | |
| Hydrochloric Acid SCHEMBL2076633 | 0.87 | USP2 (0.35) | USP2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL2077783 | 0.87 | USP2 (0.34) | USP2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL2077833 | 0.87 | USP2 (0.34) | USP2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL2078688 | 0.87 | USP2 (0.34) | USP2ALDH1A1TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351751-A1 | Substituted pyrazolopyrimidines | CEPHALON, INC. (US) | 2011-08-03 | — | — | EP | disclosed |