Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896470 | 1.00 | KMT2A (0.48) | KMT2AMAPTKDM4CKDM4APHF8 | |
| SCHEMBL26105510 | 0.98 | KMT2A (0.45) | KMT2AMAPTKDM4CKDM4APHF8 | |
| SCHEMBL8899009 | 0.91 | KMT2A (0.59) | KMT2AMAPTFFAR4FFAR1ALDH1A1 | |
| SCHEMBL27587028 | 0.91 | KMT2A (0.59) | KMT2AMAPTFFAR4FFAR1ALDH1A1 | |
| SCHEMBL27706217 | 0.91 | KMT2A (0.59) | KMT2AMAPTFFAR4FFAR1ALDH1A1 | |
| SCHEMBL15401153 | 0.91 | KMT2A (0.59) | KMT2AMAPTFFAR4FFAR1ALDH1A1 | |
| SCHEMBL8897363 | 0.91 | KMT2A (0.59) | KMT2AMAPTFFAR4FFAR1ALDH1A1 | |
| SCHEMBL8898488 | 0.91 | KMT2A (0.59) | KMT2AMAPTFFAR4FFAR1ALDH1A1 | |
| SCHEMBL8898013 | 0.91 | KMT2A (0.54) | KMT2AMAPTKDM4CKDM4APHF8 | |
| SCHEMBL105813 | 0.91 | MAPT (0.41) | KMT2AMAPTKDM4CKDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7887785-B2 | polysiloxanes, polysilicates; improved sunscreen protection factor; reduced irritation, improved skin feel | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-02-15 | — | — | US | claimed |
| CN-101316577-A | Personal care compositions containing silicone resins with enhanced properties and methods of making and using the same | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-12-03 | — | — | CN | claimed |
| EP-1874266-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SILICONE RESINS WITH ENHANCED PROPERTIES, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | General Electric Company (US) | 2008-01-09 | — | — | EP | claimed |
| WO-2006112865-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SILICONE RESINS WITH ENHANCED PROPERTIES, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2006-10-26 | — | — | WO | claimed |
| US-20050249690-A1 | Personal care compositions with enhanced properties, method of manufacture, and method of use thereof | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-11-10 | — | — | US | claimed |
| CN-101316577-B | Personal care compositions containing silicone resins with enhanced properties and methods of making and using the same | MOMENTIVE PERFORMANCE MAT INC | 2015-07-15 | — | — | CN | disclosed |
| US-7887785-B2 | polysiloxanes, polysilicates; improved sunscreen protection factor; reduced irritation, improved skin feel | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-02-15 | — | — | US | disclosed |
| CN-101316577-A | Personal care compositions containing silicone resins with enhanced properties and methods of making and using the same | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-12-03 | — | — | CN | disclosed |
| EP-1874266-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SILICONE RESINS WITH ENHANCED PROPERTIES, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | General Electric Company (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006112865-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SILICONE RESINS WITH ENHANCED PROPERTIES, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2006-10-26 | — | — | WO | disclosed |
| US-20050249690-A1 | Personal care compositions with enhanced properties, method of manufacture, and method of use thereof | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-11-10 | — | — | US | disclosed |