Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 15/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 10/20 | 1.00 |
| ▸ | PRKCG | P05129 | 10/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 10/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 10/20 | 1.00 |
| ▸ | PRKCB | P05771 | 9/20 | 1.00 |
| ▸ | PRKCA | P17252 | 9/20 | 1.00 |
| ▸ | PRKCH | P24723 | 9/20 | 1.00 |
| ▸ | PRKCI | P41743 | 9/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 9/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 9/20 | 1.00 |
| ▸ | ROCK2 | O75116 | 7/20 | 1.00 |
| ▸ | EGFR | P00533 | 7/20 | 1.00 |
| ▸ | PRKACA | P17612 | 7/20 | 1.00 |
| ▸ | PRKACG | P22612 | 6/20 | 1.00 |
| ▸ | PRKACB | P22694 | 6/20 | 1.00 |
| ▸ | SRC | P12931 | 4/20 | 1.00 |
| ▸ | CHEK1 | O14757 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | KDR | P35968 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Staurosporine SCHEMBL13780401 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL14554228 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL13168061 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL23768489 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL12245439 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL23793206 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| SCHEMBL12304513 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| SCHEMBL24393902 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL21312855 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL13621639 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9463426-B2 | Methods and systems for coating particles | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-7976823-B2 | Controlling particle size; ferromagnetic particles in polymer matrix; heating, releasing therapeutic agent | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-7858183-B2 | increase in internal pressure eventually causes particle to burst (particle containing a gas generator e.g. water or saline), forming burst particle, and it releases ferromagnetic particles to deliver to unhealthyl tissue; drug delivery system | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-7622530-B2 | Drug delivery compositions and medical devices containing block copolymer | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080045654-A1 | POLYMER PARTICLES INCLUDING COVALENTLY BONDED CHEMICAL SPECIES | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-02-21 | — | — | US | disclosed |