Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 18/20 | 0.52 |
| ▸ | CTSG | P08311 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311357 | 0.88 | CMA1 (0.64) | CMA1CTSGMEN1KMT2ACYP1A2 | |
| SCHEMBL12432915 | 0.88 | CMA1 (0.52) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL8118090 | 0.84 | CMA1 (0.54) | CMA1CTSGMEN1KMT2ACYP1A2 | |
| SCHEMBL2313676 | 0.84 | CMA1 (0.53) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2313253 | 0.84 | CMA1 (0.58) | CMA1CTSGMEN1KMT2ACYP1A2 | |
| SCHEMBL12431829 | 0.82 | CMA1 (0.46) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2311444 | 0.80 | CMA1 (0.55) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2312188 | 0.80 | CMA1 (0.65) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2309949 | 0.80 | CMA1 (0.55) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2312449 | 0.78 | CMA1 (0.70) | CMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152674-B1 | BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2011-08-03 | — | — | EP | disclosed |