Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.57 |
| ▸ | PDE4A | P27815 | 13/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | PDE1A | P54750 | 1/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.57 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2526103 | 0.88 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL12432123 | 0.85 | PDE4B (0.68) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2528061 | 0.85 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL8005716 | 0.84 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2527995 | 0.84 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL8005096 | 0.83 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2528591 | 0.83 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL8007303 | 0.81 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL7995515 | 0.81 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2531380 | 0.81 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4DCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094450-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC (US) | 2011-08-04 | — | — | WO | disclosed |