Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16230005 | 0.89 | TSHR (0.52) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL16883176 | 0.79 | TSHR (0.48) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL24058856 | 0.79 | TSHR (0.44) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL22561787 | 0.78 | TSHR (0.61) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| Bicarbonate SCHEMBL17603242 | 0.78 | TSHR (0.55) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5271678 | 0.78 | TSHR (0.55) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL12158351 | 0.78 | TSHR (0.55) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL800995 | 0.77 | TSHR (0.60) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2759326 | 0.75 | TSHR (0.44) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL10785382 | 0.75 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981444-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-7981444-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-20070244296-A1 | Dendritic Polymers with Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244296-A1 | Dendritic Polymers with Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-10-18 | — | — | US | disclosed |