SCHEMBL124340

SCHEMBL124340

CN1CC(=O)N(C)CC1=O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 7/20 0.43
CRBN Q96SW2 1/20 0.43
BRD2 P25440 1/20 0.43
PIK3CD O00329 1/20 0.41
KMT2A Q03164 2/20 0.38
PLA2G7 Q13093 1/20 0.32
GSK3A P49840 3/20 0.32
GSK3B P49841 3/20 0.32
MMP2 P08253 1/20 0.31
CREBBP Q92793 1/20 0.31
POLB P06746 1/20 0.31
ADRA2C P18825 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19546202 1.00 BRD4 (0.43) BRD4CRBNBRD2PIK3CDKMT2A
SCHEMBL19546734 1.00 BRD4 (0.43) BRD4CRBNBRD2PIK3CDKMT2A
SCHEMBL14544573 1.00 BRD4 (0.43) BRD4CRBNBRD2PIK3CDKMT2A
SCHEMBL13298015 1.00 BRD4 (0.43) BRD4CRBNBRD2PIK3CDKMT2A
SCHEMBL12748060 0.92
SCHEMBL17433534 0.83 BRD4 (0.56) BRD4CRBNBRD2PIK3CDKMT2A
SCHEMBL25120414 0.79 POLB (0.34) BRD4CRBNBRD2PIK3CDPOLB
SCHEMBL19546268 0.79 PIK3CD (0.35) BRD4CRBNBRD2PIK3CDPOLB
SCHEMBL13155014 0.79 PIK3CD (0.39) BRD4CRBNBRD2PIK3CD
SCHEMBL19546266 0.79 PIK3CD (0.35) BRD4CRBNBRD2PIK3CDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536598-B New synthesis method of 1, 4-dimethyl-2, 5-piperazine dione compound 青岛科技大学 2024-04-02 CN claimed
CN-117658838-A Novel method for synthesizing sarcosine 青岛科技大学 2024-03-08 CN claimed
CN-115536598-A Novel synthesis method of 1,4-dimethyl-2,5-piperazinedione compound 青岛科技大学 2022-12-30 CN claimed
US-9878975-B2 Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides EVONIK DEGUSSA GMBH (DE) 2018-01-30 US claimed
US-20160223908-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2016-08-04 US claimed
US-9341949-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2016-05-17 US claimed
US-20140322647-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF SUMITOMO BAKELITE CO., LTD (JP) 2014-10-30 US claimed
US-5614217-A Capsule shell formulation to produce brittle capsules R.P. SCHERER CORPORATION (US) 1997-03-25 US claimed
EP-0672036-A1 PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES XENOVA LIMITED (GB) 1995-09-20 EP claimed
EP-0471592-B1 Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids DOW CHEMICAL CO (US) 1995-08-09 EP claimed
EP-0552360-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-07-28 EP claimed
WO-1993003825-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO claimed
US-5167941-A Sulfur dioxide; cationic polyelectrolyte stabilizers THE DOW CHEMICAL COMPANY (US) 1992-12-01 US claimed
US-5098681-A Piperaznes having carbonyl groups THE DOW CHEMICAL COMPANY (US) 1992-03-24 US claimed
EP-0471592-A2 Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids THE DOW CHEMICAL COMPANY (US) 1992-02-19 EP claimed
US-4766149-A SYNERGISTIC MIXTURE WITH ANTITUMOR AND ANTICARCINOGENIC AGENTS STIFTUNG DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 1988-08-23 US claimed
EP-0007597-B1 N-LOWERALKYL-GLYCINAMIDES AND SARCOSINE ANHYDRIDE AND THEIR MIXTURES WITH KNOWN TUMOR-INHIBITING COMPOUNDS, SARCOSIN FOR USE IN THE TREATMENT OF TUMORS, MEDICAMENTS CONTAINING THESE COMPOUND AND PROCESSES FOR THEIR PREPARATION Stiftung Deutsches Krebsforschungszentrum (DE) 1985-01-16 EP claimed
EP-4707391-A1 NUCLEIC ACID COMPOUNDS FOR ZPI INHIBITION e-therapeutics PLC (GB) 2026-03-11 EP disclosed
EP-0007597-A1 N-loweralkyl-glycinamides and sarcosine anhydride and their mixtures with known tumor-inhibiting compounds, sarcosin for use in the treatment of tumors, medicaments containing these compound and processes for their preparation Stiftung Deutsches Krebsforschungszentrum (DE) 1980-02-06 EP disclosed
US-4140791-A DOWNY MOLDEW, PHYTOPHTHORA CROWN AND ROOT ROT CHEVRON RESEARCH COMPANY (US) 1979-02-20 US disclosed