Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319370 | 0.85 | TSHR (0.75) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL11659781 | 0.84 | TSHR (0.53) | TSHRTHRBHSD17B10TDP1ALDH1A1 | |
| SCHEMBL20001266 | 0.83 | TSHR (0.72) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL12255565 | 0.82 | TSHR (0.60) | TSHRTHRBALDH1A1 | |
| SCHEMBL17489178 | 0.82 | TSHR (0.64) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL2156739 | 0.80 | TSHR (0.62) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL1902015 | 0.80 | TSHR (0.62) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL8067583 | 0.80 | TSHR (0.49) | TSHRTHRBHSD17B10TDP1ALDH1A1 | |
| SCHEMBL21843129 | 0.80 | TSHR (0.49) | TSHRTHRBHSD17B10TDP1ALDH1A1 | |
| SCHEMBL14922216 | 0.80 | TSHR (0.49) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735509-B2 | Use of polyorganosiloxanes in the processing and vulcanisation of rubber | Schill + Seilacher “Struktol” GmbH (DE) | 2014-05-27 | — | — | US | disclosed |
| US-8436098-B2 | Use of polyorganosiloxanes in the processing and vulcanization of rubber | Schill + Seilacher “Struktol” GmbH (DE) | 2013-05-07 | — | — | US | disclosed |
| US-20130046059-A1 | USE OF POLYORGANOSILOXANES IN THE PROCESSING AND VULCANISATION OF RUBBER | SCHILL + SEILACHER "STRUKTOL" GMBH (DE) | 2013-02-21 | — | — | US | disclosed |
| US-20110178249-A1 | USE OF POLYORGANOSILOXANES IN THE PROCESSING AND VULCANIZATION OF RUBBER | SCHILL + SEILACHER "STRUKTOL" GMBH (DE) | 2011-07-21 | — | — | US | disclosed |