Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435049 | 0.96 | SYK (0.79) | SYK | |
| SCHEMBL10196385 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL10196390 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL10196351 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL10196357 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL524190 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL524189 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL10196591 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL523102 | 0.83 | SYK (1.00) | SYK | |
| SCHEMBL523103 | 0.83 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092128-A1 | SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS SYK KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |