Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | XIAP | P98170 | 18/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12128047 | 0.89 | MME (0.48) | MMEACEXIAP | |
| SCHEMBL1328852 | 0.85 | XIAP (0.49) | MMEACEXIAP | |
| SCHEMBL12127829 | 0.77 | MME (0.46) | MMEACEXIAP | |
| SCHEMBL12435340 | 0.76 | XIAP (0.53) | XIAP | |
| SCHEMBL12433658 | 0.76 | XIAP (0.60) | XIAP | |
| SCHEMBL12434417 | 0.76 | XIAP (0.57) | XIAP | |
| SCHEMBL1330906 | 0.76 | MME (0.46) | MMEACEXIAP | |
| SCHEMBL1328679 | 0.75 | MME (0.47) | MMEACEXIAP | |
| SCHEMBL1330685 | 0.75 | MME (0.46) | MMEACEXIAP | |
| SCHEMBL1329443 | 0.73 | MME (0.52) | MMEACEXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989441-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-08-02 | — | — | US | disclosed |
| US-20090069294-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069294-A1 | Organic Compounds | XIAP, BAX, MCL1 | MME 3989/4885ACE 3425/4885XIAP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.