Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27283973 | 1.00 | PIK3CD (0.41) | PIK3CDKDM4ECHRM5ADRA2CBCHE | |
| SCHEMBL18427493 | 1.00 | PIK3CD (0.41) | PIK3CDKDM4ECHRM5ADRA2CBCHE | |
| SCHEMBL18664005 | 0.88 | PIK3CD (0.44) | PIK3CDPOLBACHE | |
| SCHEMBL19501163 | 0.88 | PIK3CD (0.44) | PIK3CDPOLBACHE | |
| SCHEMBL24765448 | 0.86 | PIK3CD (0.42) | PIK3CDKDM4ECHRM5ADRA2CPOLB | |
| SCHEMBL27284601 | 0.86 | BCHE (0.34) | PIK3CDKDM4EBCHEPOLB | |
| SCHEMBL21369254 | 0.85 | KDM4E (0.42) | KDM4ECHRM5ADRA2CBCHEACHE | |
| SCHEMBL23374535 | 0.85 | PIK3CD (0.39) | PIK3CDKDM4ECHRM5ADRA2CPOLB | |
| SCHEMBL26345081 | 0.85 | PIK3CD (0.41) | PIK3CDKDM4ECHRM5ADRA2CPOLB | |
| SCHEMBL10076884 | 0.83 | BCHE (0.42) | KDM4EBCHECARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058149-A1 | TRICYCLIC PYRAZOL AMINE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-05-19 | — | — | WO | disclosed |