Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29686979 | 0.85 | AKR1B1 (0.44) | KDM4EAKR1B1MEN1KMT2AGABRR1 | |
| SCHEMBL19975190 | 0.85 | AKR1B1 (0.44) | KDM4EAKR1B1MEN1KMT2AGABRR1 | |
| SCHEMBL27997592 | 0.81 | KDM4E (0.44) | KDM4EAKR1B1HSD17B10CYP2C19KMT2A | |
| SCHEMBL27543528 | 0.78 | AKR1B1 (0.41) | KDM4EAKR1B1GABRR1ALDH1A1PTGDR2 | |
| SCHEMBL27654199 | 0.77 | TDP1 (0.44) | KDM4EHTTAKR1B1HSD17B10ALDH1A1 | |
| SCHEMBL17300098 | 0.76 | KDM4E (0.61) | KDM4EPKMHTTHSD17B10MEN1 | |
| SCHEMBL21736916 | 0.76 | S1PR4 (0.49) | KDM4EHTTHSD17B10MEN1CYP2C9 | |
| SCHEMBL8234812 | 0.75 | AKR1B1 (0.39) | KDM4EAKR1B1CYP2C9ALDH1A1PTGDR2 | |
| SCHEMBL4917922 | 0.75 | MEN1 (0.55) | KDM4EPKMHTTHSD17B10MEN1 | |
| SCHEMBL3018109 | 0.74 | KDM4E (0.41) | KDM4EAKR1B1CYP2C19GABRR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095997-A1 | BENZAMIDE COMPOUNDS AS GLUCOKINASE ACTIVATORS AND THEIR PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-08-11 | — | — | WO | disclosed |