Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066303 | 1.00 | PREP (0.42) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL889338 | 0.94 | KCNK3 (0.41) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL12436928 | 0.94 | PREP (0.41) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL12436556 | 0.94 | PREP (0.41) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL16062559 | 0.94 | KCNK3 (0.41) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL18426928 | 0.94 | KCNK3 (0.41) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL12436927 | 0.92 | PREP (0.41) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL16062569 | 0.90 | PREP (0.40) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL16020769 | 0.90 | PREP (0.37) | PREPCHRM2CHRM1CHRM3KAT2B | |
| SCHEMBL16020770 | 0.90 | PREP (0.37) | PREPCHRM2CHRM1CHRM3KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091532-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |