SCHEMBL12436724

SCHEMBL12436724

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nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 13/20 0.49
CTSD P07339 4/20 0.49
DPP4 P27487 1/20 0.48
DPP8 Q6V1X1 1/20 0.48
DPP9 Q86TI2 1/20 0.48
BACE2 Q9Y5Z0 3/20 0.47
ENPEP Q07075 5/20 0.46
MME P08473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30123079 0.96 DPP4 (0.51) BACE1CTSDDPP4DPP8DPP9
SCHEMBL29531593 0.96 DPP4 (0.51) BACE1CTSDDPP4DPP8DPP9
SCHEMBL30728886 0.96 DPP4 (0.51) BACE1CTSDDPP4DPP8DPP9
SCHEMBL31181278 0.95 BACE1 (0.53) BACE1CTSDDPP4DPP8DPP9
SCHEMBL31234146 0.91 BACE1 (0.51) BACE1CTSDDPP4DPP8DPP9
SCHEMBL31064920 0.89 BACE1 (0.48) BACE1CTSDDPP4DPP8DPP9
SCHEMBL30220502 0.88 BACE1 (0.49) BACE1CTSDBACE2ENPEP
SCHEMBL6386178 0.88 DPP4 (0.54) BACE1CTSDDPP4DPP8DPP9
SCHEMBL30997439 0.88 DPP4 (0.54) BACE1CTSDDPP4DPP8DPP9
SCHEMBL30053992 0.88 PDCD1LG2 (0.48) BACE1CTSDBACE2ENPEPMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119686702-A Gas storage injection and production collaborative operation method 中国石油天然气股份有限公司 2025-03-25 CN claimed
CN-119321294-A Salt cavern gas storage brine discharge and water mixing salt accumulation prevention system and operation method thereof 中国石油化工股份有限公司 2025-01-17 CN claimed
US-20240301003-A1 PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX NONO INC. (CA) 2024-09-12 US claimed
CN-118143897-A Method suitable for online maintenance of emergency cut-off valve of high-sulfur-content gas field 中国石油化工股份有限公司 2024-06-07 CN claimed
US-11878044-B2 Combination therapy for ischemia NONO INC. (CA) 2024-01-23 US claimed
EP-4274596-A1 PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX NoNO Inc. (CA) 2023-11-15 EP claimed
CN-116897051-A Plasmin peptides for increasing therapeutic index 诺诺公司 2023-10-17 CN claimed
WO-2022150655-A1 PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX NONO INC. (CA) 2022-07-14 WO claimed
CN-215635067-U ESDV valve 中国石油化工股份有限公司 2022-01-25 CN claimed
CN-118143897-B Method suitable for online maintenance of emergency cut-off valve of high-sulfur-content gas field 中国石油化工股份有限公司 2026-05-05 CN disclosed
US-20260118363-A1 Application of GLUN2A and NMDA Receptor Containing GLUN2A as Targets in Screening Drugs for Treating Depression SYNPHATEC SHANGHAI BIOPHARMACEUTICAL TECH CO LTD (CN) 2026-04-30 US disclosed
EP-4706670-A1 PSD-95 DOMAIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) 2026-03-11 EP disclosed
US-12471388-B2 Semiconductor device SOCIONEXT INC. (JP) 2025-11-11 US disclosed
US-12459814-B2 Steam reforming JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2025-11-04 US disclosed
US-20160176924-A1 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION UNIVERSITY OF COPENHAGEN (DK) 2016-06-23 US disclosed
US-20160176924-A1 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION UNIVERSITY OF COPENHAGEN (DK) 2016-06-23 US disclosed
US-9241967-B2 Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction UNIVERSITY OF COPENHAGEN (DK) 2016-01-26 US disclosed
US-9241967-B2 Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction UNIVERSITY OF COPENHAGEN (DK) 2016-01-26 US disclosed
US-20110178022-A1 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION UNIVERSITY OF COPENHAGEN (DK) 2011-07-21 US disclosed
US-20110178022-A1 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION UNIVERSITY OF COPENHAGEN (DK) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118363-A1 Application of GLUN2A and NMDA Receptor Containing GLUN2A as Targets in Screening Drugs for Treating Depression GRIN2A, GRIN2B, GRIN2C BACE1 811/4885CTSD 2199/4885DPP4 1602/4885
US-20160176924-A1 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION PSD, GRIN1, GRIN3B BACE1 792/4885CTSD 2493/4885DPP4 1418/4885
US-20110178022-A1 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION GRIN1, PSD, GRIN3B BACE1 834/4885CTSD 2491/4885DPP4 1392/4885
US-11878044-B2 Combination therapy for ischemia PSD, DAPK2, FABP7 BACE1 650/4885CTSD 1531/4885DPP4 653/4885
US-20240301003-A1 PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX DAO, DNPEP, DDO BACE1 270/4885CTSD 601/4885DPP4 718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.