⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13913818 | 1.00 | — | — | |
| SCHEMBL13249306 | 1.00 | — | — | |
| SCHEMBL13248670 | 0.97 | — | — | |
| SCHEMBL10032053 | 0.87 | — | — | |
| SCHEMBL29245833 | 0.83 | — | — | |
| SCHEMBL7183267 | 0.83 | — | — | |
| SCHEMBL29245830 | 0.83 | — | — | |
| SCHEMBL29245955 | 0.83 | — | — | |
| SCHEMBL29245914 | 0.83 | — | — | |
| SCHEMBL2512714 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094708-A2 | SMALL MOLECULES FOR THE MODULATION OF MCL-1 AND METHODS OF MODULATIING CELL DEATH, CELL DIVISION, CELL DIFFERENTIATION AND METHODS OF TREATING DISORDERS | DANA-FARBER CANCER INSTITUTE, INC (US) | 2011-08-04 | — | — | WO | disclosed |
| US-20090204128-A1 | DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS | NEOTRACT, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-7429117-B2 | Camera-mounted dimmable lighting apparatus | LITEPANELS LLC (US) | 2008-09-30 | — | — | US | disclosed |