SCHEMBL12437882

SCHEMBL12437882

CCCC1CCCC2OC12

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
ADRA2A P08913 2/20 0.33
ADRA2B P18089 2/20 0.33
ADRA2C P18825 2/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21391306 0.86
SCHEMBL9643577 0.86 EPHX1 (0.38) CA1CA2CA4
SCHEMBL4190841 0.84 EPHX1 (0.41)
SCHEMBL24567416 0.84 EPHX1 (0.41)
SCHEMBL4190845 0.84 EPHX1 (0.41)
SCHEMBL723707 0.82
SCHEMBL9298380 0.78
SCHEMBL1149309 0.78
SCHEMBL9649898 0.78
SCHEMBL12164136 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399541-A1 ADDITION CURABLE LIQUID SILICONE RUBBER COMPOSITION FOR FLAME RETARDANT AIRBAG SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-14 US disclosed
US-10551566-B2 Method of preparing an optical connector and optical devices comprising the optical connector prepared thereby DOW SILICONES CORPORATION (US) 2020-02-04 US disclosed
US-20170107331-A1 Methods For Preparing Articles And Associated Articles Prepared Thereby DOW CORNING CORPORATION (US) 2017-04-20 US disclosed
US-20160349455-A1 METHOD OF PREPARING AN OPTICAL CONNECTOR AND OPTICAL DEVICES COMPRISING THE OPTICAL CONNECTOR PREPARED THEREBY DOW SILICONES CORPORATION 2016-12-01 US disclosed
US-20160349455-A1 METHOD OF PREPARING AN OPTICAL CONNECTOR AND OPTICAL DEVICES COMPRISING THE OPTICAL CONNECTOR PREPARED THEREBY DOW SILICONES CORPORATION 2016-12-01 US disclosed
US-20160102226-A1 Curable Composition, Method Of Preparing Cured Article, And Cured Article Formed Thereby DOW SILICONES CORPORATION 2016-04-14 US disclosed
WO-2016003636-A1 METHODS FOR PREPARING ARTICLES AND ASSOCIATED ARTICLES PREPARED THEREBY DOW CORNING CORPORATION (US) 2016-01-07 WO disclosed
US-9091809-B2 Integrated planar polymer waveguide for low-loss, low-crosstalk optical signal routing DOW CORNING CORPORATION (US) 2015-07-28 US disclosed
US-20140369643-A1 Integrated Planar Polymer Waveguide For Low-Loss, Low-Crosstalk Optical Signal Routing DOW SILICONES CORPORATION 2014-12-18 US disclosed
WO-2014186549-A1 METHOD OF PREPARING AN ARTICLE AND ARTICLE PREPARED THEREBY DOW CORNING CORPORATION (US) 2014-11-20 WO disclosed
WO-2014186514-A1 CURABLE COMPOSITION, METHOD OF PREPARING CURED ARTICLE, AND CURED ARTICLE FORMED THEREBY DOW CORNING CORPORATION (US) 2014-11-20 WO disclosed
US-8885994-B2 Integrated planar polymer waveguide for low-loss, low-crosstalk optical signal routing DOW CORNING CORPORATION (US) 2014-11-11 US disclosed
US-8885994-B2 Integrated planar polymer waveguide for low-loss, low-crosstalk optical signal routing DOW CORNING CORPORATION (US) 2014-11-11 US disclosed
EP-1692209-B1 ACTIVE ENERGY RAY-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION, LIGHT-TRANSMITTING COMPONENT, AND METHOD FOR MANUFACTURING THE LIGHT-TRANSMITTING COMPONENT DOW CORNING TORAY CO LTD (JP) 2013-10-02 EP disclosed
US-20110176764-A1 INTEGRATED PLANAR POLYMER WAVEGUIDE FOR LOW-LOSS, LOW-CROSSTALK OPTICAL SIGNAL ROUTING DOW CORNING CORPORATION (US) 2011-07-21 US disclosed
US-20110176764-A1 INTEGRATED PLANAR POLYMER WAVEGUIDE FOR LOW-LOSS, LOW-CROSSTALK OPTICAL SIGNAL ROUTING DOW CORNING CORPORATION (US) 2011-07-21 US disclosed
US-7771794-B2 Active energy ray-curable, organopolysiloxane resin composition, light-transmitting component, and method for manufacturing the light-transmitting component DOW CORNING CORPORATION (US) 2010-08-10 US disclosed
EP-1761586-B1 ACTIVE ENERGY RAY-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION, OPTICAL TRANSMISSION COMPONENT, AND MANUFACTURING METHOD THEREOF DOW CORNING TORAY CO LTD (JP) 2010-02-10 EP disclosed
US-20080058441-A1 Active Energy Ray-Curable, Organopolysiloxane Resin Composition, Light-Transmitting Component, And Method For Manufacturing The Light-Transmitting Component DOW TORAY CO., LTD. (JP) 2008-03-06 US disclosed