Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438489 | 0.87 | IGF1R (0.61) | IGF1R | |
| SCHEMBL12438527 | 0.86 | IGF1R (0.64) | IGF1R | |
| SCHEMBL15109563 | 0.81 | IGF1R (0.59) | IGF1R | |
| SCHEMBL14311369 | 0.79 | IGF1R (0.37) | IGF1R | |
| SCHEMBL14320036 | 0.79 | IGF1R (0.45) | IGF1R | |
| SCHEMBL14161978 | 0.77 | IGF1R (0.61) | IGF1R | |
| SCHEMBL14050611 | 0.75 | IGF1R (0.46) | IGF1R | |
| SCHEMBL4009664 | 0.75 | IGF1R (1.00) | IGF1R | |
| SCHEMBL3929737 | 0.74 | IGF1R (1.00) | IGF1R | |
| SCHEMBL12439793 | 0.73 | IGF1R (0.62) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841760-B1 | PYRIMIDINE DERIVATIVES AS KINASE MODULATORS AND METHOD OF USE | EXELIXIS INC (US) | 2011-08-10 | — | — | EP | disclosed |